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At International Seminar last year, we introduced a new compounding base to help pharmacies creating customized medications for dermatology as well as cosmeceuticals: W06™ Anhydrous Topical Base. While there are already some high-performing dermatological bases, such as Clarifying™ and XemaTop™, we also wanted to develop an anhydrous option for compounding pharmacies.
W06 has a water activity below 0.6 (Aw < 0.6), which is where it gets its name, and which classifies it as an anhydrous base. This allows for prolonged default beyond-use dates (BUDs). We have also tested and shown W06 to be able to accommodate sensitive active pharmaceutical ingredients, such as hydroquinone and ascorbic acid.
As with any great base for dermatology and cosmeceutical compounding, W06 also has an elegant, refined feel, and its emollient properties moisturize and soften the skin as it delivers active pharmaceutical ingredients.
We have already developed and tested over 35 formulas with W06, and we will continue to create more. PCCA members can access them here.
We still recommend that compounders consider Clarifying in formulations for patients with acne and rosacea, and XemaTop in formulations for patients with psoriasis, eczema and dry skin. We have several XemaTop-based formulas with extended BUDs that have been studied using stability-indicating methods. But for compounders who need prolonged BUDs for formulas that do not have stability studies behind them, or who are working with sensitive ingredients, we recommend using W06.
If PCCA members have questions about compounding with W06 Anhydrous Topical Gel, they can contact our Pharmacy Consulting Department at 800.331.2498.
These statements are provided for educational purposes only. They have not been evaluated by the Food and Drug Administration, and are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment.