In the world of pharmacy compounding, troches have been a staple dosage form for decades. These patient-specific, medicated lozenges—typically compounded with polyethylene glycol or gelatin—have allowed compounding pharmacies to help patients with diverse needs from hormone replacement therapy to dental and ear, nose and throat applications. However, there haven’t been major improvements in this dosage form for some time, and increasingly, pharmacists, prescribers and patients are also looking for options with natural ingredients.

This is why we developed NataTroche™, the first proprietary troche base made with natural ingredients and free of polyethylene glycol or gelatin. It also has a pleasant texture similar to chocolate that patients will like.

Perhaps most important, though, is the taste. NataTroche has a subtle sweetness and flavor, and it masks bitter drugs very well by itself, including progesterone. For many formulations, compounders won’t have to add additional ingredients to adjust the flavor. This means that NataTroche is easier and more efficient for them, and it creates a better experience for their patients.

We’ve already developed and tested over 70 formulas with NataTroche, and we’ll continue to create more. PCCA members can access them here.

Benefits for Compounders

• Easy to Work With
  Its emulsifying properties improve solubilization and make it easier to incorporate active pharmaceutical ingredients
• Saves Time
  Many NataTroche formulations will not require additional ingredients to be weighed and added, such as sweeteners, flavors, silica gel, xanthan gum or acacia
• Broad Application
  It has an ideal melting point of 55–61° C, allowing compounders to use a wide variety of active pharmaceutical ingredients, and allowing the troches to be stored at room temperature

Benefits for Patients

• Better Taste and Texture
  NataTroche’s proprietary formula offers a pleasant taste with a texture similar to chocolate while masking bitter flavors better than other troche bases
• Enhanced Delivery
  It dissolves faster than polyethylene glycol or gelatin troche bases, and its lipid composition improves contact time with oral mucosa, therefore potentially improving absorption
• Natural-Ingredient Option
  It’s a great option for patients or prescribers who would prefer compounds with natural ingredients
• Convenience
  It’s anhydrous, allowing for long beyond-use dates at room temperature and less-frequent prescription refills

If PCCA members have questions about compounding with NataTroche, they can contact our Clinical Services department at 800.331.2498.

These statements are provided for educational purposes only. They have not been evaluated by the Food and Drug Administration, and are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment.